Osteoarthritis and osteoporosis image analysis research is yet another focus area of IIBI. Architecture and biomechanics of osteoporotic bone, cartilage morphometrics, and overall orthopedic biomechanics are studies from a variety of imaging modalitries, including MR, CT, and ultrasound.
Characterization of trabecular bone plate-rod micro-architecture
CT-Based Modeling of Bone Micro-Architecture and Fracture-Risk
Osteoporosis in Chronic Obstructive Pulmonary Disease (COPD)
understanding the linkage between COPD-related factors, bone structure, and fracture risk and identification of unique COPD subgroups with elevated fracture-risk
3D cartilage MR segmentation -- normal and osteoarthritic joints, note cartilage thinning and ``holes'' in the right-most image. Right panel: Simultaneous 4D knee MR bone+cartilage segmentation - 8 time-point 3D datasets registered and simultaneously segmented in 4D.